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闭经患者的细胞遗传学分析
引用本文:胡明洁,熊素梅. 闭经患者的细胞遗传学分析[J]. 蚌埠医学院学报, 2002, 27(2): 103-104. DOI: 10.3969/j.issn.1000-2200.2002.02.004
作者姓名:胡明洁  熊素梅
作者单位:蚌埠医学院,生物学教研室,安徽,蚌埠,233003
摘    要:分析闭经患者的异常核型形成的可能原因及其与临床症状的关系.方法:对78例闭经患者进行外周血染色体标本作常规分析.结果:共发现染色体异常28例,占全部被检者35.90%.其中原发性闭经46 例,检出异常核型25例(54.35%);继发性闭经32例,检出异常核型3例(9.38%).结论:对原发性闭经患者应常规行外周血染色体检查,以明确闭经的原因 ,及早对症治疗;继发性闭经尤其是25岁以下的患者也应及时进行染色体检查.

关 键 词:闭经  细胞遗传学
文章编号:1000-2200(2002)02-0103-02
修稿时间:2001-07-06

The cytogenetics analysis of 78 patients with amenorrhea
HU Ming jie,XIONG Su mei. The cytogenetics analysis of 78 patients with amenorrhea[J]. Journal of Bengbu Medical College, 2002, 27(2): 103-104. DOI: 10.3969/j.issn.1000-2200.2002.02.004
Authors:HU Ming jie  XIONG Su mei
Abstract:Objective:To analye the important cause of abnormal karyotype forming of patients with amenorrhea and the relationship between abnormal karyotype and clinical symptoms.Methods:The blood chromosome specimen of 78 cases with amenorrhea were analysed using standand technique.Results:Among 78 cases with amenorrhea,28 cases with abnormal chromosome were detected,accounting for 35.90% within all cases.Twenty five(54.35%) of 46 cases with primary amenorrea were abnormal karyotype;while 3(9.38%) of 32 cases with secondary amenorrea were abnormal karyotype.Conclusions:The cases with primary amenorrhea should be taken for a routine chromosome examination and early expectant treatment.Chromosome examination should also be taken in cases with secondary amenorrea in time,especially under the age of 25.
Keywords:amenorrhea  cytogenetics
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