93例传染性非典型肺炎患者胸部X线转归相关因素分析

目的　探讨传染性非典型肺炎临床治愈后胸部X线转归的相关因素。方法　选定年龄、性别、起病时体温、病变波及范围、开始使用激素治疗时间作为可能的相关因素 ,对 93例治愈出院的SARS患者 ,根据其出院时普通胸片检查结果做回顾性分析 ,对所得数据采用卡方检验进行统计学处理。结果　胸片表现未完全恢复正常者中男性 19例 (5 4 2 9% ) ,女性 16例 (4 5 71% ) ,P >0 0 1;年龄 4 5岁以上者 7例 (5 8 33% ) ,年龄 4 5岁以下者 2 8例 (34 5 7% ) ,P >0 0 1;起病表现为高热者 (体温≥39℃ ) 2 6例 (5 0 0 0 % ) ,起病表现为低热或中等程度发热者 9例 (2 1 95 % ) ,P <0 0 1;病变波及双侧肺野 ,或为单侧多发病灶者 2 2例 (5 2 38% ) ,单侧单发病灶者 13例 (2 5 4 9% ) ,P <0 0 1;开始使用激素治疗病程 5d之内者 2 2例 (38 6 0 % ) ,病程 5d以后开始使用激素治疗者 12例 (33 33% ) ,P >0 0 1。病程 7d之内开始使用激素治疗者 2 1例 (30 0 0 % ) ,病程 7d以后者 14例 (6 0 87% ) ,P <0 0 1。结论　肺部病变的最终转归主要与病情本身的严重程度有关 (在临床上表现为起病时高热 ,胸片提示病变波及双侧肺野 ) ,而与患者性别、年龄无明显相关性。过早使用激素治疗 (病程 5d之内 ) ,对肺部病变的最终转归

Analysis on factors related to X-ray outcomes in 93 SARS patients

OBJECTIVE: To study the related factors of the X-ray outcomes in recovered SARS patients. METHODS: The X-ray results of 93 patients with SARS were studied retrospectively. The possible related factors analyzed were age, sex, body temperature at onset, range of the lesion, glucocorticoid administration time. The data were analyzed by chi square test. RESULTS: Among all the patients with abnormal X-ray result, 19 were male (54.29%), 16 (45.71%) were female, P > 0.01; 7 (58.33%) were above the age of 45; 28 (34.57%) were below the age of 45, P > 0.01; hyperpyrexia (>/= 39), 26 (50.00%), below 39, 9 (21.95%); multiple-lesion, 22 (52.38%), mono-lesion, 13 (25.49%), P < 0.01; glucocorticoid administration time within 5 days, 22 (38.60%) after 5 days, 12 (33.33%), P > 0.01; within 7 days, 21 (30.00%), after 7 days, 14 (60.87%), P < 0.01. CONCLUSION: The X-ray results of SARS were closely related to the severity of the disease (hyperpyrexia and bilateral lung field lesion). There was no significant correlation between X-ray result and the age or sex of the patients. Early use of glucocorticoid (within 5 days after onset), had no remarkable influence on the X-ray result. It was noted, however, the incidence of residual lesion in lung obviously increased if glucocorticoid was administered after 7 days of onset.