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CA19-9、CA242和CA50联检对胰腺癌诊断的价值
引用本文:易丹,殷跃.CA19-9、CA242和CA50联检对胰腺癌诊断的价值[J].放射免疫学杂志,2009,22(4):328-330.
作者姓名:易丹  殷跃
作者单位:湖南省人民医院核医学科,410005
摘    要:目的:探讨联检肿瘤标志物CA19-9、CA242和CA50在胰腺癌诊断中的应用价值。方法:选择2007年1月~2008年10月湖南省人民医院门诊及住院患者共250人进行了CA19-9、CA242和CA50联检,其中120例为临床明确诊断的胰腺癌患者。结果:胰腺癌患者血清中的CA19-9、CA242和CA50水平明显高于对照组。CA19-9敏感性和特异性分别为82.0%和79.6%;CA242敏感性和特异性分别为78.5%和81.6%;CA50敏感性和特异性分别为52.7%和74.6%;联检CA19-9、CA242和CA50其敏感性和特异性提高为96.82%和98.75%。结论:采用CA19-9、CA242和CA50联检的方法,对胰腺癌的早期诊断具有一定的临床意义。

关 键 词:胰腺癌  肿瘤标志物  敏感性  联合检测

Diagnostic Value of Combined Determinations of Serum CA19-9,CA242 and CA50 Levels in Patients with Pancreatic Cancer
Yi Dan,Yin Yue.Diagnostic Value of Combined Determinations of Serum CA19-9,CA242 and CA50 Levels in Patients with Pancreatic Cancer[J].Journal of Radioimmanology,2009,22(4):328-330.
Authors:Yi Dan  Yin Yue
Institution:Yi Dan,Yin Yue Department of Nuclear Medicine,People's Hospital of Hunan Province(410005),China
Abstract:Objective To explore the diagnostic value of combined determinations of serum CA19-9,CA242 and CA50 levels in patients with pancreatic cancer.Methods Serum CA19-9,CA242 and CA50 levels were determined with RIA in 120 patients with pancreatic cancer,50 patients with chronic pancreatitis and 80 controls.Results The serum levels of CA19-9,CA242 and CA50 in patients with pancreatic cancer were significantly higher than those in patients with pancreatitis and controls.With CA19-9,the diagnostic sensitivity and s...
Keywords:pancreatic cancer  tumor marker  sensitivity  combination assay  
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