夜间长时间血液透析对尿毒症患者营养状态的影响

Objective To observe the influence of nocturnal prolonged hemodialysis (INHD) on patients' nutrition status. Methods Thirty-two maintenance hemodialysis patients received INHD(3 times per week and 7.5 hours each session) and thirty-five maintenance hemodialysis patients received conventional hemodialysis(3 times per week and 4 hours each session) as control were observed for 6 months. The nutrition status of these patients on various aspects which concluded physical measurements, laboratory tests, and dietary record at baseline(0 month) and exit(6 months) were recorded. Results (1)There were no differences in age,sex,body weight,and primary diseases between two groups. (2)The body weight, triceps skinfold thickness(TSF), and hand grip strength increased at exit point, but no statistical difference compared with the control group. Mid-upper arm circumference(MAC) increased signicantly from (27.1±4.2) to (30.5±6.1) cm (P<0.05). Compared with the control group (26.9±3.4) cm, there was a significant difference (P<0.05). (3)Serum phosphate decreased significantly from (0.5±0.5) to (0.1±0.6) ?滋mol/L (P=0.001) in INHD group. (4)The nutrition status were improved in INHD group evaluated by subjective global assessment (SGA)(P=0.03). (5) Dietary intake was recorded by a 3-day food record. Dietary intake of energy, protein, lipid, calcium, potassium, and phosphate increased in INHD group. None of the differences achieved statistical significance between two groups. Conclusion As compared with conventional hemodialysis, INHD can increase the dietary intake, decrease serum phosphate level, and improve patients nutrition status.

Influence of nocturnal prolonged hemodialysis on nutrition status in uremic patients