Evidence-based treatments in pemphigus vulgaris and pemphigus foliaceus |
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| Authors: | Frew John W Martin Linda K Murrell Dédée F |
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| Institution: | aSt George Hospital, Gray Street, Kogarah, Sydney, NSW 2217, Australia;bFaculty of Medicine, University of Sydney, Sydney, NSW 2006, Australia;cSt John's Institute of Dermatology, St Thomas' Hospital, London SE17EH, England, UK;dDepartment of Dermatology, St George Hospital, University of New South Wales, Gray Street, Kogarah, Sydney, NSW 2217, Australia |
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| Abstract: | Treatment modalities in pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are many and varied, although level 1 evidence supporting their use is limited. To date, only 2 systematic reviews exist to support the use of different treatment modalities to control this group of conditions. Overall, within the literature, the quality of trials comparing treatment modalities is poor. Cohort sizes are small, methodologies are varied, and standardized outcome measurements are lacking. The authors aim to present a comprehensive view of the level 1 evidence that exists for common treatment modalities used in PV and PF. |
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| Keywords: | Pemphigus Evidence-based medicine Immunosuppressive therapy Immunomodulating therapy |
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