Sonographic abnormalities in idiopathic restless legs syndrome (RLS) and RLS in Parkinson's disease |
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Authors: | Ryu Jung Ho Lee Myung Sik Baik Jong Sam |
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Affiliation: | Department of Neurology, Sanggye Paik Hospital, Inje University College of Medicine, 761-1, Sanggye 7 dong, No won gu, Seoul 139-707, Republic of Korea. |
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Abstract: | We aimed to investigate and compare sonographic abnormalities in the substantia nigra (SN) in patients with idiopathic restless legs syndrome (iRLS), those with RLS and Parkinson's disease (RLS-PD), those with idiopathic Parkinson's disease (iPD), and healthy controls. Study participants totaled 60 patients with RLS (41 iRLS, 19 RLS-PD), 25 iPD patients, and 35 age-matched healthy controls. Comparing all groups, the SN region's echogenicity area in the iRLS patients was significantly decreased compared with that in the PD-RLS, iPD, and control groups (p < 0.0001), and the PD-RLS group demonstrated a significantly increased echogenicity area compared with the control group (p < 0.05) and iRLS group (p < 0.0001). We found that the RLS-PD group's sonological results and clinical findings were different from those of the iRLS group. |
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