空腹血葡萄糖和糖化血红蛋白在Ⅱ型糖尿病诊断中的价值

目的探究并分析空腹血葡萄糖(FPG)和糖化血红蛋白(HbA1c)在Ⅱ型糖尿病(2DM)诊断中的价值。方法选取来院检查的经确诊为Ⅱ型糖尿病患者100例(A组)及非糖尿病患者100例(B组),对两组患者进行空腹血糖及糖化血红蛋白的测定,分别计算空腹血葡萄糖和糖化血红蛋白检测的特异度和灵敏度情况,分析并比较空腹血糖和糖化血红蛋白在Ⅱ型糖尿病诊断中的准确度。结果 A组FPG对Ⅱ型糖尿病诊断灵敏度为99%,特异度为93%,HbA1c诊断灵敏度为95%,特异度为92%,空腹血糖和糖化血红蛋白诊断的灵敏度和特异度无明显差异(P>0.05)。B组FPG诊断灵敏度和特异度仅为7.0%和1.0%;HbA1c诊断灵敏度和特异率为8.0%和5.0%。结论糖化血红蛋白与空腹葡萄糖在Ⅱ型糖尿病诊断的特异度和灵敏度无明显差异,均具有较高的诊断价值,值得在临床上广泛应用。

The contrast and analysis about the value of fasting plasma glucose and HbA1c on diagnosis of type 2 diabetes mellitus

Objective To explore and analyze the value of fasting plasma glucose （FPG） and HbA1c on the diagnosis of type 2 diabetes mellitus.Methods 100 patients with type 2 diabetes and 100 patients without type 2 diabetes were included in the present study.Fasting blood sugar and HbA1c of patients were tested.The specificity and sensitive of fasting blood sugar and HbA1c were counted.The accuracy of fasting blood sugar and HbA1c on type 2 diabetes mellitus were analyzed.Results The sensitive of FPG on type 2 diabetes mellitus diagnose was 99％ and the specificity was 93％.The sensitive of HbA1c diagnose wss 95％ and the specificity was 92％.The specificity and sensitive of fasting blood sugar and HbA1c were no difference and they were similar to the diagnosis standard （P＞0.05）.Conclusion The specificity and sensitive of HbA1c in clinical diagnosis of type 2 diabetes and fasting blood sugar in the diagnosis of diabetes are significant difference.The result is agreeable to practical situation and has high diagnosis value.