| 各型冠心病纤溶酶原及血小板聚集功能的临床意义 |
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| 引用本文： | 严秉智,黄健群,焦克荣,张成勋,许克诚,孙作鹏,刘作芳. 各型冠心病纤溶酶原及血小板聚集功能的临床意义[J]. 中国医科大学学报, 1987, 0(3) |
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| 作者姓名： | 严秉智 黄健群 焦克荣 张成勋 许克诚 孙作鹏 刘作芳 |
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| 作者单位： | 中国医科大学附属第一医院内科(严秉智，黄健群，焦克荣，张成勋，许克诚)，中国医科大学附属第一医院内科实验室(孙作鹏)，中国医科大学附属第一医院内科实验室(刘作芳) |
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| 摘 要： | 本文总结了纤溶酶原、血小板集聚功能在不同类型冠心病的改变。结果:①纤溶酶原在不稳定型心绞痛组和陈旧性心肌梗塞组较正常组明显降低,急性心肌梗塞组与正常组相比,差别尤为显著。②血小板最大聚集率在陈旧性心肌梗塞组高于不稳定型心绞痛组。在急性心肌梗塞组连续三次检测中显示聚集率有逐渐增高趋势。
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| 关 键 词： | 冠状动脉疾病 纤溶酶原 血小板凝集 |
CLINICAL SIGNIFICANCE OF PLASMINOGEN AND PLATELET AGGREGATION RATE IN VARIOUS TYPES OF CORONARY HEART DISEASE |
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| Yan Bingzhi et al. CLINICAL SIGNIFICANCE OF PLASMINOGEN AND PLATELET AGGREGATION RATE IN VARIOUS TYPES OF CORONARY HEART DISEASE[J]. Journal of China Medical University, 1987, 0(3) |
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| Authors: | Yan Bingzhi et al |
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| Affiliation: | Yan Bingzhi et al Department of Medicine,The First Affiliated Hospital |
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| Abstract: | In the present study the concentration of blood plasminogen and the maxi-mum aggregation rate of platelet were determined in 64 patients with coronaryheart disease (unstable angina pectoris(UAP)15 cases, acute myocardial infarc-tion(AMI) 30 cases, old myocardial infarction (CMI) 19 cases and 29 normalsubjects as controls. It was found that the blood plasminogen level in UAPand OMI was lower than that in controls (P<0.05), particularly, the concen-tration of plasminogen significantly reduced in AML (P>0.01), on the otherhand, the maximum aggregation rate of platelet in OMI was greater than thatin UAP (P<0.05). The results showed that the changes of blood plasminogenlevel and the maximum aggregation rate of platelet might relate to involvingcoronary heart disease.So the trials of anticoagulants and platelet-active drugsare based on theassumption that benefit is achieved by preventing either theonset of infarction or the secondary attack. |
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| Keywords: | Coronary heart disease Plasminogen platelet aggregationrate |
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