160例肺周围型占位病变超声引导下穿刺组织活检临床分析

目的 探讨超声引导下经皮肺穿刺活检术在肺周围型占位病变诊断中的应用价值.方法 回顾性分析2010年6月～2013年8月于首都医科大学附属北京友谊医院就诊的160例接受超声引导下穿刺活检的肺周围型占位患者病理结果,分析病理诊断阳性率,对比良恶性病变的发病率、不同性别患者的恶性发病率及良恶性病变的最大前后径的差异性.结果 160例患者穿刺活检病理诊断阳性率为93.8％ （150/160）;恶性发病率为71.9％（115/160）,良性发病率为21.9％（35/160）,恶性发病率显著高于良性,男性的恶性发病率与女性相比,差异无统计学意义（P＞0.05）;恶性占位的平均最大前后径为（3.22±1.19）cm,良性占位的平均最大前后径为（3.06±1.25）cm,二者比较差异无统计学意义（t=0.663,P＞0.05）.结论 超声引导下经皮肺穿刺活检诊断肺周围型占位病变安全,有效,阳性率高,并发症少,有较高的临床应用价值.

Clinical analysis of ultrasound guided puncture biopsy of 160 cases with pulmonary peripheral space-occapying lesions

Objective To access the value of ultrasound-guided biopsy for the diagnosis of peripheral pulmonary nodules.Methods 160 cases of pathological results from Beijing Friendship Hospital during June 2010 to August 2013 were analyzed retrospectively.The cases were all peripheral pulmonary nodules biopsy using ultrasound-guided puncture.The positive rate of pathological diagnosis,the morbidity of benign and malignant cases,the morbidity of different sex,and the difference of maximum anteroposterior diameter between benign and malignant lesions were analyzed and compared separately.Results The positive rate of pathological diagnosis was 93.8% （150/160） in 160 cases.The morbidity of benign and malignant cases were 21.9% （35/160） and 71.9% （115/160） respectively; the malignant lesions were statistically significantly more than the benign lesions,the morbidity of men had no statistically significant with women （P 〉 0.05）; the maximum anteroposterior diameter of benign lesions was （3.06±1.25） cm,and that of malignant lesions was （3.22±1.19） cm,which had no statistically significant （t =0.663,P 〉 0.05）.Conclusion The ultrasound-guided biopsy reveals advantage of high positive rate,more efficiency and lower side effect in the diagnosis of peripheral pulmonary nodules.It may be widely used in the clinical practice.