| 神经干细胞的来源 |
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| 引用本文： | 李钢,柯以铨. 神经干细胞的来源[J]. 中华神经医学杂志, 2003, 2(5): 399-400,F003 |
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| 作者姓名： | 李钢 柯以铨 |
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| 作者单位： | 1. 海口市人民医院神经外科,海南,海口,570208
2. 第一军医大学珠江医院全军神经医学研究所,广东,广州,510282 |
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| 基金项目： | 广东省重大组织工程项目(粤财企2001-367) |
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| 摘 要： | 神经干细胞是近年来神经科学领域研究的一个热点。神经干细胞可来源于胚胎干细胞和成年干细胞，前者包括早期胚胎细胞和胎儿神经组织细胞，由于从胚胎获取干细胞面l临伦理学的束缚，从成年来源的神经干细胞将是未来临床应用更具可行性的途径。成年来源的神经干细胞包括存在于成年神经组织中的干细胞和从其他组织中分化得到的干细胞，其中骨髓基质细胞具有多分化潜能，在适当的条件下可以诱导分化出神经干细胞，目前备受关注。
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| 关 键 词： | 神经干细胞 来源 胚胎干细胞 成年干细胞 骨髓基质细胞 神经系统疾病 |
| 文章编号： | 1671-8925(2003)05-399-03 |
The source of neural stem cells |
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| LI Gang,KE Yiquan. The source of neural stem cells[J]. Chinese Journal of Neuromedicine, 2003, 2(5): 399-400,F003 |
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| Authors: | LI Gang KE Yiquan |
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| Affiliation: | LI Gang,KE YiquanDepartment of Neurosurgery,Haikou People's Hospital,Haikou 570280,China, Deuromedical Institute of PLA,Zhujiang Hospital,First Military Medical University,Guangzhou 510282,China |
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| Abstract: | Neural stem cell (NSC) is recently one of the cutting-edge fields in neuroscience research. NSC is derived from embryonic stem cells(ESC), including cells from the early embryo, neural cells of the fetus, and adult stem cells. Adult stem cells possess a potential in clinical application in that clinical use of embryonic tissues will always face the ethical problem. Adult NSC can be isolated from the adult nerve tissue or derived from the stem cells of other tissue. Marrow stromal cells (MSC) isolated from bone marrow have been paid much attention as they are multipotent and can differentiate into NSC if cultured with suitable condition. |
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| Keywords: | neural stem cell marrow stromal cells adult stem cells embryonic stem cells |
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