Myasthenia gravis associated with HTLV-I infection and atypical brain lesions |
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Authors: | Lalive Patrice H Allali Gilles Truffert André |
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Affiliation: | Department of Neurosciences, Clinic of Neurology, University Hospital of Geneva, Micheli-du-Crest 24, 1211 Geneva 14, Switzerland. patrice.lalive@hcuge.ch |
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Abstract: | We report a patient who experienced progressive diplopia and distal weakness of the upper limbs. Magnetic resonance imaging of the brain showed extensive white matter lesions and analysis of cerebrospinal fluid revealed acute human T-lymphotropic virus type I (HTLV-I) infection. Myasthenia gravis (MG) was evidenced by electromyography (EMG) and antibodies against acetylcholine receptor. This unusual case of MG associated with HTLV-I infection and brain-restricted lesions underscores the possible link between viruses and MG pathogenesis. |
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Keywords: | human T‐lymphotropic virus type‐I–associated myelopathy tropical spastic paraparesis human T‐lymphotropic virus type I meningitis myasthenia gravis |
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