| 单磷酸阿糖腺苷联合白细胞介素-2、乙肝免疫球蛋白、乙肝疫苗治疗慢性乙型肝炎效果观察 |
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| 引用本文： | 张义红,吴子文,饶中柱,叔宝珠,王小聪.单磷酸阿糖腺苷联合白细胞介素-2、乙肝免疫球蛋白、乙肝疫苗治疗慢性乙型肝炎效果观察[J].临床军医杂志,2004,32(1):38-40. |
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| 作者姓名： | 张义红 吴子文 饶中柱 叔宝珠 王小聪 |
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| 作者单位： | 解放军第457医院,传染科,湖北,武汉,430012 |
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| 摘 要： | 目的 研究单磷酸阿糖腺苷 (Ara AMP)联合白细胞介素 2 (IL 2 )、乙肝免疫球蛋白 (HBIG)、乙肝疫苗治疗慢性乙型肝炎的临床疗效。方法 选择 68例慢性乙型肝炎患者分为两组 ,治疗组用 (Ara AMP联合IL 2、HBIG、乙肝疫苗 ,对照组用干扰素α 2a ,评估两组肝功能及乙肝病毒复制近、远期疗效。结果 两组ALT复常率、HBeAs及HBVDNA阴转率均无明显差异 (P >0 .0 5 )。结论 Ara AMP联合IL 2、HBIG、乙肝疫苗治疗慢性乙型肝炎抗乙肝病毒的效果肯定。
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| 关 键 词： | 慢性乙型肝炎 单磷酸阿糖腺苷 白细胞介素-2 乙肝免疫球蛋白 乙肝疫苗 干扰素α-2a |
| 文章编号： | 1671-3826(2004)01-0038-03 |
| 修稿时间： | 2003年11月17 |
Clinical Observation on Arabinosyladenosine Monophsphate with Interleurin-2 Hepatitis B Immunoglobulin Hepatitis B vaccine in Treatment of Chronic Hepatitis B |
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| Zhang yi-hong,Wu Zi-wen,Rao Zhong-zhu,Shu Bao-zhu,Wang Xiao-cong.Clinical Observation on Arabinosyladenosine Monophsphate with Interleurin-2 Hepatitis B Immunoglobulin Hepatitis B vaccine in Treatment of Chronic Hepatitis B[J].Clinical Journal of Medical Officer,2004,32(1):38-40. |
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| Authors: | Zhang yi-hong Wu Zi-wen Rao Zhong-zhu Shu Bao-zhu Wang Xiao-cong |
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| Abstract: | Objective To evaluate the clinical efficasy of arabinosyladenosine monophsphate(Ara-Amp) woth interleurin-2(IL-2) hepatitis B immunoglobulin(HBIG) hepatitis B vaccine on chronic hepatits B patients.Methods Selected 68 cascs with chronic hepatitis B were divided into two groups: Ara-Amp wih IL-2. HBIG hepatitis B vaccine in treatmen group, interferon alpfa-2a(IFNα-2a) in control group.Results ALT recovery,HBeAg and HBVDNA negative-transformed rates had no difference beween two groups (P>0.05).Conclusion It preliminarily proved Ara-Amp with lL-2 HBIG hepatitis B vaccine efficacy in the treatment of chronie hepatitis B for fighting against HBV. |
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| Keywords: | chronic hepatitis B arabinosyladenosine monophosphate interleurin-2 hepatitis B immunoglobulin hepatitis B vaccine interferon alpfa-2a |
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