中药"克炎痛"镇痛作用的实验观察

目的 研究中药“克炎痛”的镇痛作用。方法 采用两种急性痛测痛方法（电刺激鼠尾-嘶叫法，钾离子透入-甩尾法），两种病理性痛测痛方法（福尔马林试验和佐剂性关节炎局部测痛）和一种内脏痛模型（扭体反应）。结果 克炎痛对急性痛和由福尔马林引起的局限性炎症痛有确切的镇痛作用。并以醋提制剂的镇痛作用更明显，而对关节炎炎症局部痛和内脏痛并无镇痛作用。另外，此药有一定的毒性作用。结论 中药克炎痛对急性疼痛有较好的镇痛消肿功效。但只能外用。

Experimental Observation on the Analgesic Effect of a Compound of Chinese Traditional Drugs Keyantong

Objective To study the analgesic effect of Keyantong which was made of Chinese traditional drugs.Methods Two tests for the acute pain (tail electric stimulation-vocalization test and K +-iontophoresis tail flick test),two tests for pathological pain (formalin test and localized adjuvant arthritis) and a model of visceral pain (writhing responses) were used.Results Keyantong elicited a definite analgesic effect on the acute experimental pain and the localized inflammatory pain induced by formalin.This effect was better with the vinegar-extracted compound.However,no significant analgesic effects of Keyantong were observed on the localized pain resulted from the arthritic inflammation and the visceral pain.In addition,this compound was considered to have some degree of toxicity.Conclusion Keyantong has a good analgesic and swelling-alleviating effects on the acute pain,but it can be used only by external application on skin.