首页 | 本学科首页   官方微博 | 高级检索  
检索        

左卡尼汀对老年维持性血液透析患者炎症、营养不良和贫血的影响研究
引用本文:薛海燕.左卡尼汀对老年维持性血液透析患者炎症、营养不良和贫血的影响研究[J].陕西医学杂志,2013(12):1611-1612.
作者姓名:薛海燕
作者单位:陕西省第四人民医院血液净化中心,西安710043
摘    要:目的:探讨左卡尼汀(L-CN)对老年维持性血液透析(MHD)患者炎症、营养不良和贫血的影响。方法:46例老年MHD患者随机分为两组,对照组予常规治疗,观察组加用左卡尼汀,比较两组患者治疗前后血IL-6、hs-CRP、Alb、PAB、Hb、HCT等指标的差异。结果:治疗12周后,观察组患者血清IL-6、hs-CRP较治疗前显著下降,Alb、PAB、Hb、HCT显著上升,对照组Hb、HCT较治疗前显著上升,差异有统计学意义(P〈O.05),但明显低于观察组,差异有统计学意义(P〈0.05);对照组治疗后血IL-6、hs-CR及Alb、PAB与治疗前比较无统计学差异(P〉0.05)。结论:老年MHD患者普遍存在L-CN缺乏,L-CN治疗可以改善患者微炎症及营养不良状态,纠正肾性贫血.

关 键 词:肾透析  并发症  炎症  营养障碍  @左卡尼汀

Impact of L-carnitine on microinflammation,malnutrition and anemia in elderly patients with maintenance hemodialysis
Xue Haiyan.Impact of L-carnitine on microinflammation,malnutrition and anemia in elderly patients with maintenance hemodialysis[J].Shaanxi Medical Journal,2013(12):1611-1612.
Authors:Xue Haiyan
Institution:Xue Haiyan(Department of blood purification center,The fourth people's hospital of shaanxi (xi'an 710043 ) )
Abstract:Objective:To investigate the impact of L-carnitine on microinflammation, malnutrition and a- nemia in elderly patients with maintenance hemodialysis(MHD) . Methods:46 elderly MHD patients were randomly divided into two groups, the control group received conventional treatment, the observation group were treated with L-carnitine, the serum IL-6, hs-CRP, AIb, PAB, Hb, HCT were compared. Results:After 12 weeks, the levels of serum IL-6, hs-CRP were decreased significantly than before treatment, the Atb, PAB, Hb, HCT were increased , and in the control group the Hb, HCT were increased , the difference was of statistically significant (P〈0.05), but the Hb, HCT was significantly lower than that in the observation group(P 〈0.05) ; there was no significant differ- ence in control group after treatment in serum IL-6, hs-CR and Alb, PAB (P〉 0.05). Conclusion:MHD patients with low levels of L-CN, and L-CN therapy can improve micro-inflammation and malnutrition status and renal anemia.
Keywords:Renal dialysis/complicatios  Inflammation  Nutrition disorders  @L-carnitine
本文献已被 维普 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号