实时三维超声心动图评价冠心病合并2型糖尿病患者的右心功能

目的:应用实时三维超声心动图(real-time three-dimentional echocardiography,RT-3DE)定量评价冠心病合并2型糖尿病患者的右心功能.方法:门诊及住院患者,分3组:冠心痛组(CHD组)16例,糖尿病组(DM组)20例,冠心痛合并糖尿病组(CHD+ DM组)27例,同时选取24例门诊体检健康者作为正常对照组(NC组).对入选者应用RT-3DE行三维容积成像,并应用四维右室功能(4D- RVF)分析软件计算右室整体舒张末期容积(RVEDV)、收缩末期容积(RVESV)及射血分数(RVEF),分别进行各组间比较.结果:与NC组比较,CHD组、DM组及CHD+ DM组的RVEDV及RVESV明显增大(P＜0.05),RVEF无显著差异(P=0.31).结论:CHD、DM及CHD+ DM患者即使常规超声心动图检查结果为右室内径正常、右室收缩功能无明显变化,但是其容积与正常对照组比较已增大.

Real-Time Three-Dimensional Echocardiography in Evaluating Right Ventricular Function in Diabetic Patients with or without Coronary Heart Disease

Objective：To quantitatively evaluate the right ven tricular function coronary heart disease patients with or without type 2 diabetes mellitus using real-time three-dimensional echocardiography（RT-3DE）.Methods：Sixty-three patients were enrolled. They were classified into three groups：coronary heart disease group（CHD group,n = 16）,type 2 diabetes mellitus group（DM group,n = 20）,and coronary heart disease with type 2 diabetes mellitus group（CHD ＋ DM group,n = 27）.The control group（NC group） included 24 healthy volunteers.All the patients underwent tranditional echocardiography and realtime three-dimensional echocardiography（RT-3DE） examination.The overall right ventricular end-diastolic volume（RVEDV）, end-systolic volume（RVESV） and ejection fraction（RVEF） were calculated by right ventricular function（4D-RVF） analysis software.Results：Compared with control group,RVEDV,RVESV in CHD group,DM group and CHD ＋ DM group increased significantly（P〈0.05） even though RVEF had no statistical differences among 4 groups（P = 0.31）.Conclusions： The capacity of right ventricle of patients in CHD group,DM group and CHD ＋ DM group enlarged obviously detected by RT-3DE while LVEF were all at normal range.