非血液系统肿瘤并发贫血530例临床分析

目的分析非血液系统肿瘤患者并发贫血的发生率、贫血程度及贫血时红细胞形态。方法对2009年1月·至；2011年3月在我院住院的530例非血液系统肿瘤患者的临床资料进行回顾性分析。结果非血液系统肿瘤患者贫血的发生率达20．94％（111／530），消化系统肿瘤贫血发生率最高35．3％（65／184），妇科肿瘤19．4％（6／31），肺癌18．3％（34／186），泌尿生殖系统肿瘤6．8％（5／74），乳腺癌1．8％（1／55）。不同病种的贫血发生率比较差异有统计学意义（X^2=44．9785，P〈0．01）。其中Ⅰ、Ⅱ度贫血发生率15．66％，Ⅲ、Ⅳ贫血发生率5．28％，多发生于消化道肿瘤患者。男性贫血患者72例，占22．36％；女性贫血患者39例，占18．75％；不同性别之间贫血发生率比较差异无统计学意义（X^2=1．0020，P〉0．05）。贫血愈重，红细胞体积愈小。出院有贫血诊断的仅2．08％，采取治疗措施的5．66％。结论非血液系统肿瘤患者贫血发生率较高，多呈小细胞性，常不引起医患双方注意，治疗率低。

Clinical analysis of anemia in 530 patients with tumor

Objective To analyze the incidence,severity and morphologic characteristics of anemia in patients with malignant tumors. Methods Five hundred and thirty hospitalized patients with a primary diagnosis of tumor were enrolled in this study at our hospital from Jan. 2009 to Mar. 2011. Their hemoglobin （Hb） levels, age, sex, and type of tumor were recorded. Anemia was diagnosed to be present when their Hb on admission was less than 110 g/L. Results There were tll in the 530 patients （20. 94% ） had anemia on admission. Anemia was seen in 35.3% of patients with digestive system cancer,in 19. 4% with gynecologic cancers,in 18.3% with lung cancers,in 6. 8% with urinogenital cancers and 1.8% with breast cancers. The difference of incidence of anemia in different types of cancers was statistically significant （X2 = 44. 9785, P 〈 0. 01 ）. Grade Ⅰ and Ⅱ anemia accounted for 15.66% ; and grade Ⅲ and Ⅳ accounted for 5.28% of all. There was no significant difference of incidence of anemia between male and female [22. 36% （72/322） vs. 18.75% （39/208）, X2 = 1. 0020,P 〉0.05 ]. The more severe the anemia was, the smaller the erythrecyte mean corpuscular volume was. The rate of anemia was 2. 08% when patients were discharged,and 5.66% were intervened. Conclusion The incidence of anemia was high in patients hospitalized with tumor, but only a small percent got enough medical care.