| 静脉心肌声学造影观察心肌微血管缺血再灌注损伤的实验研究 |
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| 引用本文： | 陈小林,查道刚,刘伊丽,贾满盈,黄晓波,谢晋国,苏伟.静脉心肌声学造影观察心肌微血管缺血再灌注损伤的实验研究[J].南方医科大学学报,1997(4). |
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| 作者姓名： | 陈小林 查道刚 刘伊丽 贾满盈 黄晓波 谢晋国 苏伟 |
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| 作者单位： | 南方医院心内科!广州市510515 |
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| 摘 要： | 为探讨急性心肌缺血再灌注后心肌微血管状态，观察了三条开胸犬前降支（LAD）阻断前后，心肌声学造影显示的心肌微血管对Ach反应情况、结果表明：LAD阻断30min再开放后，心肌微血管灌注于血流重建后90min才恢复。说明心肌微血管内皮损伤是心肌顿抑的原因之一
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| 关 键 词： | 静脉心肌声学造影 缺血再灌注 时间－强度曲线 |
Experimental study on myocardial ischemic reperfusion injury with transvenous myocardial contrast echocardiography |
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| Chen Xiaolin, Zha Daogang, Liu Yili, Jia Manying, Huang Xiaobo, Xie Jinguo,Su Wei.Experimental study on myocardial ischemic reperfusion injury with transvenous myocardial contrast echocardiography[J].Journal of Southern Medical University,1997(4). |
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| Authors: | Chen Xiaolin Zha Daogang Liu Yili Jia Manying Huang Xiaobo Xie Jinguo Su Wei |
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| Abstract: | To observe the myocardial microvascular per fusion after coronary flow restore from total obstruc-tion, three open-chest dbgs underwent intravenous MCE combined with intraaortic Ach injection beforeLAD obstruction and immediate, 15, 30, 60, 90 minutes after re-opening of LAD from 30 minute total ob-struction. The result showed that myocardial microvascular perfusion restored until 90 minutes after LADre-opening in all 3 dogs- This study suggested that myocardial microvascular injury may be the direct causeof myocardium stunning and MCE is a very good technique to study this phenomenon. |
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| Keywords: | transvenous myocardial contrast echocardiography ischemic reperfusion time-intensity curve |
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