| 1型和2型糖尿病视网膜病与血管紧张素Ⅰ转换酶基因多态性关联研究 |
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| 引用本文： | 武守山,邢朝斌,张娟.1型和2型糖尿病视网膜病与血管紧张素Ⅰ转换酶基因多态性关联研究[J].中国优生与遗传杂志,2005,13(1):29-30. |
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| 作者姓名： | 武守山 邢朝斌 张娟 |
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| 作者单位： | 华北煤炭医学院生物科学系,唐山,063000 |
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| 摘 要： | 目的探讨血管紧张素Ⅰ转换酶(ACE)基因多态性与糖尿病视网膜病之间关联.方法应用PCR技术,对Ⅰ型糖尿病33名视网膜病患者、36名非视网膜病患者和2型糖尿病57名视网膜病患者、190名非视网膜病患者的ACE基因插入/缺失(Ⅰ/D)型多态性进行了检测.结果与结论未证明1型和2型糖尿病时ACE基因和视网膜病之间关联.
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| 关 键 词： | 糖尿病视网膜病 2型糖尿病 血管紧张素Ⅰ转换酶 基因多态性 |
| 文章编号： | 1006-9534(2005)01-0029-02 |
| 修稿时间： | 2004年5月13日 |
Evaluation on the relation of diabetic retinopathy and angiotensin I-converting enzyme gene polymorphism |
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| WU Shou-shan,XING Zhao-bin,ZHANG Juan..Evaluation on the relation of diabetic retinopathy and angiotensin I-converting enzyme gene polymorphism[J].Chinese Journal of Birth Health & Heredity,2005,13(1):29-30. |
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| Authors: | WU Shou-shan XING Zhao-bin ZHANG Juan |
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| Abstract: | Objective: To evaluate the relationship of angiotensin I-converting enzyme gene polymorphism and the patients with diabetic retinopathy. Methods: ACE genetic insertion/deletion(I/D) polymorphism was determined by PCR. Results and conclusion: No evidence shows that the presence of ACE gene appeared to have a association with the development of diabetic retinopathy. |
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| Keywords: | Diaberic retinopathy Type 2 diabetes Angiotensin I-converting enzyme Gene polymorphism |
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