206例药物性眼部损害文献分析

目的:探讨药物性眼部损害的特点。方法:对1998年1月～2005年12月国内医药学术期刊报道的206例有关药物性眼部损害进行统计、分析。结果:诱发眼部损害的药物以抗感染类、激素类、中枢神经系统类药物所占比例较大;眼部损害临床主要表现为青光眼、角膜炎、巩膜炎、视网膜病变、前房出血、干眼症、角膜上皮损害以及视力障碍等。结论:药物性眼部损害轻者视力下降,重者可致失明,应引起医务人员重视。

Drug - induced Impairments of Eyes:Literature Review of 206 Cases

OBJECTIVE:To discuss the characteristics of drug-induced eye impairment.METHODS:206 cases of drug-induced eye impairment reported in internal medical journals published from Jan.1998 to Dec.2005 were analyzed statistically.RESULTS:The drug-induced eye impairment was mostly induced by anti-infective drugs,hormones,nervous system drugs.The impairment was manifested predominantly by glaucoma,keratitis,scleritis;retinopathy,hyphema,xeroma,damage of corneal epithelium and visual disorder etc.CONCLUSION:Clinicians should pay great attention to the drug-induced eye impairment for it can lead to a decline in eyesight or even loss of eyesight.