昆明小鼠生长发育指标及繁殖性能测定

目的 作为我国昆明小鼠生物学特性标准化研究工作的一部分，我们承担了兰州生物制品所昆明小鼠生长发育指标及繁殖性能测定工作。方法 从生产大群中选取了170只怀孕母鼠，用其所生仔鼠进行生长发育指标的测定，测其3、7、10、14日龄窝重和3、4、5、6、8、10、12、14周龄体重。用育成雄、雌仔鼠各140只，饲养至70～75日龄配种，共配136盒，作繁殖性能测定。测初配后30d产仔率、各胎平均窝产仔数、离乳成活率和胎间隔。结果 兰生所昆明小鼠平均初生窝重为20g，反映小鼠哺乳情况的14日龄平均窝重为67．4g。公鼠10周龄时体重已达体成熟，母鼠10周龄时体重也达体成熟的90％以上。初配后30d产仔率81．6％。1～5胎平均产仔数10只以上，6～10胎平均产仔数约7只，平均离乳率84％。结论 上述结果为中国昆明小鼠标准化提供可靠数据。

Growth and Reproduction of KM Mice in the LIBP

Objective To evaluate the reproduction and growth of the Kunming(KM) mice in Lanzhou Institute of Biological Products(LIBP), as a part of the study on KM mice's biological features standardization in People's Republic of China.Methods 170 pregnant female mice were chosen from the workshop's population and the growth of the baby mice was evaluated by measuring the litter weight of 3, 7, 10, 14 days and the body weight of 3, 4, 5, 6, 8, 10, 12, 14*!weeks after birth.140 pairs of mature mice were used. Of which 136 pairs were mated within 70-75 days. The reproduction of these mice were evaluated by measuring the producing rate in 30 days after mating, the average litter number per birth, the survival rate of weaning and the time of between births.Results The average weight of newborn litter is 20g; by 14th day, the average weight of litter is 67.4g. By 10th week, the male mice weigh 39.22g,showing body-mature, and the female mice weigh 32.45g, above 90% of body-mature. The producing rate within 30 days after mating is 81.6%. The producing average of 1-5 births is above 10, the producing average of 6-10 births is about 7. The average weaning rate is 84%.Conclusion The results above could provide a reliable data for the standardization of KM in China.