首页 | 本学科首页   官方微博 | 高级检索  
     


Angiolymphoid hyperplasia with eosinophilia developing within a port wine stain
Authors:Robert N. Manton  Tinte Itinteang  Sophie de Jong  Helen D. Brasch  Swee T. Tan
Affiliation:1. Centre for the Study & Treatment of Vascular Birthmarks, Wellington Regional Plastic, Maxillofacial & Burns Unit, Hutt Hospital, Wellington, New Zealand;2. Gillies McIndoe Research Institute, Wellington, New Zealand;3. Department of Pathology, Hutt Hospital, Wellington, New Zealand
Abstract:A 19‐year‐old male with a port wine stain on the base of his neck presented with a 5‐month history of gradual thickening of the involved skin which interfered with clothing and caused repeated bleeding. The lesion was excised and histopathologic examination revealed angiolymphoid hyperplasia with eosinophilia (ALHE) arising from the pre‐existing port wine stain – a rare finding with only one previously reported case. Additionally the lesion was associated with elevated serum renin levels which virtually normalized following excision of the lesion. We further demonstrated the expression of angiotensin converting enzyme and angiotensin II receptors 1 and 2 by the lesion and discuss the possible role of the renin–angiotensin system in this condition.
Keywords:angiolymphoid hyperplasia with eosinophilia  angiotensin converting enzyme  angiotensin II receptor 1  angiotensin II receptor 2  port wine stain
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号