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Two new unsaturated fatty acids from the whole plant of Pothos chinensis
Authors:Jin-Guang Si  Hao-Li Sun  Tao Zhang  Qiu-Bo Zhang  Meng-Hua Wang  Jia-Huan Chen
Affiliation:1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China;2. School of Pharmacy, Henan University of Traditional Chinese Medicine, Zhengzhou 450008, China;3. Jiangsu HaiCi Biological Pharmaceutical Co., Ltd., Taizhou 225400, China;4. School of Pharmacy, Henan University of Traditional Chinese Medicine, Zhengzhou 450008, China;5. School of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang 110016, China
Abstract:Two new unsaturated fatty acids, (Z)-octadec-13-en-11-ynoic acid (1) and (Z)-octadec-16-en-12,14-diynoic acid (2), along with six known compounds were isolated from the whole plant of Pothos chinensis. The structures of these compounds were elucidated by detailed spectroscopic analysis, including 1D and 2D NMR data. Compound 2 showed moderate antibacterial activity against Staphylococcus aureus.
Keywords:Pothos chinensis  unsaturated fatty acids  NMR  antibacterial activity
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