Two new phenolic acids from the fruits of Forsythia suspense |
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| Authors: | Xin-Jia Yan Jing Wen Zheng Xiang Dong Cai Chong-Ning Lv Ying Zhao |
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| Affiliation: | 1. College of Pharmacy, Harbin University of Commerce, Harbin 150076, China;2. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China;3. Key Laboratory of Structure-Based Drug Design &4. Discovery (Ministry of Education), Shenyang Pharmaceutical University, Shenyang 110016, China;5. Key Laboratory of Structure-Based Drug Design &6. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China |
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| Abstract: | Two new phenolic acids forsythiayanoside C (1) and forsythiayanoside D (2), were isolated from the fruits of Forsythia suspense (Thunb.) Vahl. Their structures were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR analyses, HRESIMS and CD spectrometry. The cytotoxic and antioxidant activities testing showed that compound 2 exhibited free radical scavenging activity. |
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| Keywords: | Oleaceae Forsythia suspense phenolic acid cytotoxic activity antioxidant activity |
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