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Two new phenolic compounds and antitumor activities of asparinin A from Asparagus officinalis
Authors:Xue-Mei Li  Jin-Long Cai  Le Wang  Wen-Xiang Wang
Affiliation:1. College of Pharmacy, South-Central University for Nationalities, Wuhan 430074, China;2. School of Agriculture and Biological Technique, Yunnan Agricultural University, Kunming 650201, China
Abstract:Two new phenolic acid compounds, asparoffin C (1) and asparoffin D (2), together with four known compounds, asparenyol (3), gobicusin B (4), 1-methoxy-2-hydroxy-4-[5-(4-hydroxyphenoxy)-3-penten-1-ynyl] phenol (5), and asparinin A (6), have been isolated from the stems of Asparagus officinalis. The structures were established by extensive spectroscopic methods (MS and 1D and 2D NMR). Compound 6 has obvious antitumor activities both in vitro and in vivo.
Keywords:Asparagus officinalis  phenolic compounds  asparinin A  antitumor
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