空心针穿刺活检在口腔颌面部肿瘤的应用

目的：总结评价空心针穿刺活检在口腔颌面-头颈部肿瘤的应用。方法：回顾性分析2009年6月至2011年3月，口腔颌面-头颈部肿瘤患者47例。应用14G 或16G空心穿刺针穿刺肿瘤获取组织，进行常规病理诊断，如需要再行免疫组织化学染色。根据病理诊断决定患者治疗方案。无法得出明确肿瘤性病理诊断的、高度怀疑肿瘤者可采取切取活检或手术进行进一步检查，其他患者进行随访，计算穿刺检查的准确率。结果：穿刺活检满足临床组织病理诊断和免疫组织化学染色的需要，与术后病理及随访观察结果对照，真阳性诊断36例，真阴性9例，假阴性诊断2例，诊断准确率为95.7%。43例穿刺活检对临床治疗具有指导意义，达91.5%。未发现刺穿大血管引起出血等严重并发症，未发现穿刺针道肿瘤种植。结论：空心针穿刺活检对于口腔颌面-头颈部病变组织病理学诊断和治疗具有重要的指导意义。

Core needle biopsy in the diagnosis of oral and maxillofacial tumors

Objective: To summarize and evaluate the utility of core needle biopsy in diagnosis of head neck tumors.Methods: Lesions were performed with core needle biopsy in 47 patients who were consi-dered with tumors or other diseases in the head neck.According to the pathological diagnoses,their treating plans were made.If the pathological results could not give definite diagnoses and the lesions were considered tumors or other diseases,then operation or another biopsy was needed and,the other patients could be followed-up.The accurate rate was calculated.Results: The biopsy tissue was enough for pathological diagnosis and immunohistochemical staining.Compared with the pathological results and follow-up,positive diagnosis was in 36 cases,negative diagnosis in 9 cases,false-negative in 2 cases,and the accurate rate was 95.7%.The pathological results had guided the treatment in 43 patients,accounting for 91.5%.No serious side effects were found.Conclusion: The core needle biopsy is significant for diagnosis and treatment of head neck tumors.