过敏性皮肤病患者血清食入性和吸入性过敏原特异性IgE结果分析

目的：了解吸入性和食入性过敏原在过敏性皮肤病发病中的作用，以及环境、饮食暴露因素与患病之间的相关性。方法：采用福克过敏原特异性IgE抗体定量检测试剂盒（免疫捕获法）检测142例过敏性皮肤病患者的血清吸入性过敏原特异性IgE（包括尘螨、艾蒿、上皮组合、霉菌组合、墙草组合、花粉组合、柳树、杨树8种）和食入性过敏原特异性IgE（包括鸡蛋、牛奶、虾、羊肉、牛肉、鲤鱼、螃蟹、小麦面粉8种），并将结果以SPSS统计软件进行分析和检验。结果：吸入物以霉菌组合的阳性率高，其中过敏性皮炎组60%，湿疹组43%，荨麻疹组46%，过敏性紫癜组71%。食入物以牛奶的阳性率高，过敏性皮炎组和湿疹组的阳性率分别为42%和56%，荨麻疹组以海鲜过敏阳性率较高，为34%。暴露因素和疾病无明显相关性。结论：过敏原IgE检测为过敏性疾病的病因诊断提供了有一定价值的依据。

Analysis of serum specific IgE in aeroallergen and food allergen in patients with allergic skin diseases

Objective:To investigate the role of aeroallergen and food allergen IgE in the pathogenesis of allergen diseases and the relationship between environments,diet,exposed factors and prevalence rate in allergic skin diseases.Methods: Fooke allergen specific IgE(sIgE) antibody quantative detection kit was used to detect 142 allergen cases,including artemisia,mixture of epithelia,mixed molds,mixed botany,mixed pollens,willow,poplar,egg,milk,shrimp,mutton,beef,fish,crab,staple foods,etc.Results:Mixed molds and mixed botany were the most common allergens in the allergy dermatitis group(positive rate 60%),eczema group(43%),urticaria group(46%),and allergic purpuria group(71%).The milk revealed that it was the most common allergen in the allerge dermatitis group and eczema group(42% and 56%,respectively).While seafood was the most common allergen in the urticaria group(34%).There was no significant relationship between the exposure and prevalence rate.Conclusion:The detection of allergen IgE provides valuable basis for analysis of the cause in allergic disease.