腹腔镜联合药物治疗卵巢子宫内膜异位囊肿疗效分析

目的探讨腹腔镜联合药物治疗卵巢子宫内膜异位囊肿的疗效。方法将239例经腹腔镜保守治疗的卵巢子宫内膜异位囊肿患者分为三组：未用药物组（对照组）73例，GnRH—a组52例，孕三烯酮组114例，分析三组患者术后复发率及两种药物的副作用发生率。结果术后随访18～42个月，对照组复发率高于GnRH—a组和孕三烯酮组（P〈0，05），GnRH—a组与孕三烯酮组比较差异无统计学意义（P〉0．05），但GnRH—a组副作用发生率低于孕三烯酮组。结论腹腔镜保守治疗术后应用GnRH—a类药物或孕三烯酮胶囊均可降低卵巢子宫内膜异位囊肿复发率．但GnRH—a类药物副作用发生率明显低于孕三烯酮。

Efficacy of laparoscopic surgery and post-operation medicine for ovarian endometrioma

Objective To evaluate the efficacy of laparoscopic surgery and post-operation medicine for ovarian endometrioma.Methods All of 239 patients with ovarian endometrioma who were treated with ovarian cystectomy performed by laparoscopy were divided into three groups: untreated group,GnRH-a group,gestrinone group.The recurrence rate of the three groups and the side effects of the two kinds of medicine were compared.Results All the patients were followed up for 18 to 42 months,and the incidence of recurrence in the untreated group was higher than in GnRH-a group and gestrinone group(P < 0.05),but there was no statistically significant difference between GnRH-a group and gestrinone group(P > 0.05).The incidence of side effect in GnRH-a group was lower than gestrinone group.Conclusion Laparoscopic surgery is an effective way to treat ovarian endometrioma,and the use of GnRH-a or gestrinone after operation can reduce the incidence of recurrence,but the incidence of side effect in the gestrinone group is higher.