布托啡诺与芬太尼复合布比卡因用于硬膜外分娩镇痛的比较

目的比较布托啡诺与芬太尼复合布比卡因用于硬膜外分娩镇痛的效果。方法200例初产妇随机均分为0．12％布比卡因＋0．02mg／mL布托啡诺组（A组）和0．12％布比卡因＋2μg／mL芬太尼组（B组）。比较两组镇痛效果、Bromage评分、产程时间及Apgar评分。结果两组产妇在镇痛后30、60min视觉模拟评分低于镇痛前，镇痛效果明显，但两组间30、60min相比较视觉模拟评分无统计学意义（P〉0．05）。两组产妇Bromage评分、产程时间、分娩方式差异均无统计学意义。两组产妇均无严重不良反应。两组新生儿Apgar评分差异无统计学意义。结论布比卡因复合布托啡诺硬膜外分娩镇痛效果好，产妇和新生儿不良反应少。

A comparison of patient-controlled epidural analgesia with bupivacaine combined with Butorphanol to fentanyl for labor analgesia

Objective To compare the efficacy of patient-controlled epidural analgesia(PCEA) with bupivacaine combined with butorphanol to fentanyl for labor analgesia.Methods Two hundred pregnancy nulliparous parturients undergoing PCEA were equally randomized to receive 0.12% bupivacaine with butorphanol 0.02 mg/mL(group A) or with 2 μg/mL fentanyl(group B).The analgesia efficacy,Bromage scores,labor duration and Apgar scores were observed.Results Visual analog scale was lower than that after PCEA in groups each,it was similiar in group A than that in group B from 30 min to 60 min during PCEA(P > 0.05).There were no significant differences in Bromage scores,labor duration,labor mode and Apgar score between two groups during PCEA.No parturient had serious side effects in two groups.Conclusion PCEA with bupivacaine combined with butorphanol is as well as that with fentanyl for labor analgesia with less side effects.