MR扩散加权成像及ADC值的测量对乳腺良恶性肿瘤腋窝淋巴结的诊断价值

目的:评价扩散加权成像及ADC值的测量对腋窝良恶性淋巴结鉴别的价值.方法:收集2006-06-2008-02在我院进行乳腺动态增强扫描及扩散加权成像,有明确手术病理结果和/或针吸活检病理结果的56例共217个痛灶作为研究对象进行回顾性分析.结果:DWI可以准确判断乳腺癌腋窝淋巴结转移,47例乳腺癌中出现163个淋巴结转移,与对照组9例54个良性病变反应增生性淋巴结在DWI均表现为高信号,随b值增加信号不减低,但前者信号高于后者;前者ADC值为(1.017±0.114)×10-3mm2/s,后者ADC值为(1.905±0.136)×10-3mm2/s,两者比较有显著性差异(P<0.05).结论:MR动态增强减影技术对乳腺良恶性病灶具有较高的诊断与鉴别诊断价值.DWI和ADC值测量是一种安全、无创、准确、快速的诊断腋窝转移性淋巴结和良性反应增生性淋巴结的手段.

MR Diffusion-Weighted Imaging and ADC Value Measurement in the Diagnosis of Breast Axillary Lymph Node Cancer

Objective To value diffusion-weighted imaging and ADC value measurement of benign and malignant axillary lymph node identification value. Methods From 2006-06 to 2008--02, by collecting in the hospital for breast dynamic con-trast-enhanced scans and diffusion-weighted imaging, 217 lesions in 56 cases with a clear outcome of the surgery and pathology and/or needle biopsy results were retrospectively analyzed.Results The DWI could accurately show the lymph node of the armpit abnormality, 163 cases of 47 breast cancer cases with lymph node metastasis showed high signal in DWI image that did not decrease with increasing b value, similar to the 54 cases of 9 benign enlarged responsive prolifer-ative lymph nodes. But the former showed higher signal than the later. The ADC values were(1.017±0.114)×10-3mm2/s and (1.905±0.136)×10-3mm2/s respectively, and showed significant difference between two groups (P<0.05). Conclusion The dynamic contrast-enhanced subtraction MR technology benign and malignant breast lesions has high diagnosis and differ-ential diagnosis importance. DWI and ADC value measurement is a safe, non-invasive, accurate and rapid diagnosis of metastasis axillary lymph nodes and benign proliferative response of the lymph nodes means.