| 兔蛛网膜下腔出血后外周血中IL—2的变化及其意义探讨 |
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| 引用本文： | 邓志锋 汪泱. 兔蛛网膜下腔出血后外周血中IL—2的变化及其意义探讨[J]. 江西医学检验, 1999, 17(3): 137-139 |
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| 作者姓名： | 邓志锋 汪泱 |
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| 作者单位： | 江西医学院第二附属医院神经外科!南昌，330006，江西省医学科学研究所，江西医学院第二附属医院神经外科!南昌，330006 |
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| 摘 要： | 目的探讨免疫因素在蛛网膜下腔出血后迟发性脑血管痉挛的发生机制中的作用。方法采用兔复制动物模型，经颅多普勒监测血管痉挛发生情况，实验前后检测外周血IL－2活性。结果实验组动物迟发性脑血管痉挛的发生率达84．62％；实验第7天实验组外周血中IL－2活性较实验前显著增高（P＜0．01）。结论在蛛网膜下腔出血后迟发性脑血管痉挛的发生机制中确有免疫因素的参与。
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| 关 键 词： | 蛛网膜下腔出血 脑血管痉挛 白细胞介素－2 |
Changes in IL-2 of the preipheral blood and its significance follwing subarachnoid hemorrhage in the rabbits |
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| Deng Zhifeng, Wang Yang, Zhang Mingiven.. Changes in IL-2 of the preipheral blood and its significance follwing subarachnoid hemorrhage in the rabbits[J]. Jiangxi Journal of Medical Laboratory Sciences, 1999, 17(3): 137-139 |
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| Authors: | Deng Zhifeng Wang Yang Zhang Mingiven. |
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| Abstract: | Objective To investigatc the effect of immune factors on the mechanism ofpathogenesis in delayed cereblal vasospasm (DCVS) following suharechnoid hemorrhage(SAH).Method Rabbits were uscd to produce models of SAH and transcranial doppler ultrasound wasused to monitor the occurience of cerebrovasospasm. The IL - 2 in peripheral blood was examinedbefore and after the experiment. Results The incidence of DCVS was 84. 26%, and the level ofIL - 2 in peripheral blood was significantly higher on the 7th day afer experiment than that beforein the experimental group(P<0. 01 ). Concluson The immune factors might be involved inthe mechanism of pathogenesis DCVS following SAH. |
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| Keywords: | Subarachnoid hemorrhage Cerebrovasospasm Interleukin-2 |
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