| 头颈部鳞癌中抑癌基因PTEN的研究进展 |
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| 引用本文： | 谢思明,沈丽佳.头颈部鳞癌中抑癌基因PTEN的研究进展[J].中国病理生理杂志,2004,20(8):1531-1533. |
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| 作者姓名： | 谢思明 沈丽佳 |
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| 作者单位： | 暨南大学医学院口腔医学系，广东 广州 510632 |
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| 摘 要： | The FTEN, having a dual specificity phosphatase activity, is the first tumor suppressor gene that possess phosphatase activity hitherto. Many researches have suggested that FTEN play a major role in the tumorgenesis. In clinical, the head and neck squamous cell carcinoma(HNSCC) is one of the most common ma-lignant tumors. In this review, advances in the research of FTEN and the relationship between the PTEN and HNSCC are discussed.
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| 关 键 词： | PTEN 基因 肿瘤抑制 头颈部肿瘤 |
| 文章编号： | 1000-4718(2004)08-1531-03 |
| 收稿时间： | 2002-11-26 |
| 修稿时间： | 2002年11月26 |
Advances in the research of the tumor suppressor gene-PTEN in head and neck squamous cell carcinomas |
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| XIE Si-ming,SHEN Li-jia.Advances in the research of the tumor suppressor gene-PTEN in head and neck squamous cell carcinomas[J].Chinese Journal of Pathophysiology,2004,20(8):1531-1533. |
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| Authors: | XIE Si-ming SHEN Li-jia |
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| Institution: | Stomatology Department of Medical College, Jinan University, Guangzhou 510632, China |
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| Abstract: | The PTEN, having a dual specificity phosphatase activity, is the first tumor suppressor gene that possess phosphatase activity hitherto. Many researches have suggested that PTEN play a major role in the tumorgenesis. In clinical, the head and neck squamous cell carcinoma(HNSCC) is one of the most common malignant tumors. In this review, advances in the research of PTEN and the relationship between the PTEN and HNSCC are discussed. |
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| Keywords: | Genes tumor suppressor gene Head and neck neoplasms |
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