| 胎儿鼻骨超声检测在胎儿染色体异常诊断中的临床价值 |
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| 引用本文： | 陈文艳,郑爱娟,胡梅青.胎儿鼻骨超声检测在胎儿染色体异常诊断中的临床价值[J].中国现代医生,2013,51(4):151-152,155. |
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| 作者姓名： | 陈文艳 郑爱娟 胡梅青 |
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| 作者单位： | 陈文艳 (浙江省舟山市妇幼保健院B超室,浙江舟山,316000)； 郑爱娟 (浙江省舟山市妇幼保健院B超室,浙江舟山,316000)； 胡梅青 (浙江省舟山市妇幼保健院妇保科,浙江舟山,316000)； |
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| 基金项目： | 2009年浙江省医药卫生科学研究基金计划(B类)(项目编号：2009B159) |
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| 摘 要： | 目的探讨胎儿鼻骨超声检测在胎儿染色体异常早期诊断中的临床价值。方法选择2009年2月-2012年1月在我院进行产孕前检查的2016例孕妇进行鼻骨超声筛查，并对异常的胎儿行染色体核型分析。结果鼻骨长度随孕周增加而增加，两者呈明显正相关（r=0．75，P〈0．01），其中鼻骨长度异常的18例胎儿，14例胎儿染色体核型异常，诊断准确率高达77．78％。结论孕期进行胎儿鼻骨超声筛查在染色体异常的筛查中具有重要的临床价值。
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| 关 键 词： | 鼻骨 染色体异常 产前筛查 |
The clinic value of ultrasound in the evaluation of fetal nasal bone in chromosome abnormality |
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| Authors: | CHEN Wenyan ZHENG Aijuan HU Meiqing |
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| Institution: | 1.Department of B-Ultrasonic,The Maternal and Child Health Hospital of Zhoushan City, Zhoushan 316000, China; 2.Department of Maternal Health Care,Maternal and Child Health Hospital of Zhoushan City,Zhejiang, Zhoushan 316000, China |
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| Abstract: | Objective To investigate the clinic value of ultrasound in the evaluation of fetal nasal bone in chromosome abnormality .Methods Nasal bone ultrasound screened for 2016 pregnant women in our hospital from February 2009 to January 2012,and karyotype analysis with abnormal fetus. Results Nasal bone length increases with gestational weeks increases,both were significant positive correlation （r = 0.75 ,P 〈 0.01 ）, among 18 cases with fetal nasal bone length abnormalities,14 cases with fetal chromosomal abnormalities, diagnosis accuracy rate as high as 77.78%. Conclusion Evaluating fetal nasal bone with ultrasound in the duration of important valuable for determining chromosomal abnormality. |
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| Keywords: | Nasal bone Chromosome abnormality Antenatal screening |
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