Calciphylaxis: A condition mimicking necrotizing vasculitis |
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Authors: | M. Melikoglu S. Apaydin V. Hamuryudan S. Yurdakul N. Uygun H. Aki G. Ozbay Dr. H. Yazici |
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Affiliation: | (1) From the Division of Rheumatology, University of Istanbul, Turkey;(2) Division of Nephrology Department of Internal Medicine, University of Istanbul, Turkey;(3) Department of Pathology, Cerrahpa a Medical Faculty, University of Istanbul, Turkey |
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Abstract: | Summary A patient with end stage renal disease developed ischaemic skin necrosis and digital gangrene. He had diffuse arterial calcification associated with hyperparathyroidism secondary to renal failure. The patient received inappropriate cyclophosphamide therapy as he had been misdiagnosed as having an inflammatory vasculitis. This clinical picture, previously named calciphylaxis should come into the differential diagnosis of systemic vasculitis in a uraemic patient with hyperparathyroidism. |
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Keywords: | Vascular Calcification Soft Tissue Necrosis Hyperparathyroidism |
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