| 树鼩实验感染后血清中抗基孔肯雅病毒IgM和IgG抗体检查 |
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| 引用本文： | 张海林,米竹青,施华芳,自登云.树鼩实验感染后血清中抗基孔肯雅病毒IgM和IgG抗体检查[J].地方病通报,1997(2). |
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| 作者姓名： | 张海林 米竹青 施华芳 自登云 |
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| 作者单位： | 云南省流行病防治研究所!大理市，671000，云南省流行病防治研究所!大理市，671000，云南省流行病防治研究所!大理市，671000，云南省流行病防治研究所!大理市，671000 |
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| 摘 要： | 成年树经人工感染基孔肯雅病毒后，能产生2～6天的病毒血症。感染后第6天能产生特异性IgM抗体，第14～21天为高峰，以后逐渐下降。感染后第12天，IgG抗体开始出现，第30～60天为高峰，并持续不降，表明树对基孔肯雅病毒敏感。
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| 关 键 词： | 基孔肯雅病毒 动物模型 树鼩 病毒血症 IgM IgG |
Detection of IgM and IgG Antibodies Against Chikungunya Virus in Sera of Tree Shrews after Experiment Infection |
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| Zhang Hailin, Mi Zhuqing, Shi Huafang, Zi Dengyun.Detection of IgM and IgG Antibodies Against Chikungunya Virus in Sera of Tree Shrews after Experiment Infection[J].Endemic Diseases Bulletin,1997(2). |
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| Authors: | Zhang Hailin Mi Zhuqing Shi Huafang Zi Dengyun |
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| Abstract: | Adult tree shrews (Tupaia belangeri chinensis) have been tested by inoculation with three strains of Chikungunya (CHIK)virus isolated from Yunnan, China and Africa. These animals showed viremia for 2~6 days after injection. Specific IgM antibody appeared on the 6th day following infection and reached peak value on the 14th to 21th day. IgG antibody response occurred l2 days after infection and reached peak value on the 3O~60th day. The results indicate that tree shrew is a susceptible animal to CHIK virus, and may be used for studies of CHIK virus. |
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| Keywords: | Chikungunya virus Tree shrew Viremia IgM IgG Animal model |
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