Tei指数联合Macruz指数检测冠心病左室功能的相关研究

目的:探讨Tei指数、Macruz指数及二者联合对冠心病(CHD)患者左室收缩功能不全的诊断价值。方法:37例确诊CHD病人(CHD组)和16例冠脉造影正常者(对照组)测量Macruz指数、Tei指数和LVEF,并探讨其间关系。结果:两组间年龄无差异(P>0.05);Tei指数与LVA所测LVEF值相关(r=-0.737,P<0.01),经校正的χ2检验,χ2=0.333,P>0.05,对CHD左室收缩功能不全评价的敏感度(Se)88.2%,特异度(Sp)97.2%,Youden指数(YI)0.85。Macruz指数与LVA所测LVEF值相关(r=-0.612,P<0.01);经校正的χ2检验,χ2=1.455,P>0.05,Mac-ruz指数对CHD左室收缩功能不全评价的Se 82.4%,Sp 77.8%,YI 0.62;Tei指数联合Macruz指数对冠心病左室收缩功能不全评价的Se 97.9%,Sp 75.6%,YI 0.74。结论:Tei指数、Macruz指数是评估CHD病人左室收缩功能简单且有价值的指标,两者联合应用可提高对CHD左室收缩功能不全的诊断。

The Primary Investigation of Tei Index Combind with Macruz Index for Detecting the Left Ventricular Contractile Function in Coronary Atherosclerotic Heart Disease Patients

Objective:To investigate the value of Tei index and Macruz index for estimating left ventricular contract function in patients with coronary atherosclerotic heart disease(CHD).Methods: Tei index,Macruz index,Left ventricle ejection fraction(LVEF) were measured in 37 CHD patients and 16 healthy controls.Results:The age of two groups have no diversity(P>0.05).The Tei index and Macruz index in CHD group increased significantly compared with the control group(P<0.05,P<0.01).Tei index reflected the LVEF in all subjects(r=-0.737,P<0.01),using correction of continuity chi-square test,χ2=0.333,P>0.05.The sensitivity(Se),specificity(Sp) and Youden index(YI) of Tei index were 88.2%,97.2% and 0.85,respectively.Macruz index reflected the LVEF in all subjects(r=-0.612,P<0.01),using correction of continuity chi-square test,χ2=1.455,P>0.05.The Se,Sp and YI of Macruz index were 82.4%,77.8% and 0.62,respectively.The Se,Sp and YI of Tei index combined with Macruz index were 97.9%,75.6% and 0.74,respectively.Conclusion:Tei index and Macruz index are valuable and simple for estimating left ventricular systolic functions with high sensitivity in CHD patients.