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慢性乙型肝炎患者血清A/G、ALT/AST比值及其与病情严重程度的相关性
引用本文:向龙奎,黄砚青,何萍萍,雷幼蓉. 慢性乙型肝炎患者血清A/G、ALT/AST比值及其与病情严重程度的相关性[J]. 武汉大学学报(医学版), 1999, 20(4): 331-332
作者姓名:向龙奎  黄砚青  何萍萍  雷幼蓉
作者单位:湖北医科大学,附一医院传染科,武汉,430060
摘    要:通过对148例慢性乙型肝炎患者血清白蛋白(A)、球蛋白(G)及血清丙氨酸氨基转移酶(ALT)、门冬氨酸氨基转移酶(AST)的检测及计算A/G、ALT/AST比值,与病情轻重作相关性分析,结果提示:随着肝实质损害的加重,A/G及ALT/AST比值逐渐缩小,表现为A/G及ALT/AST呈同步变化,二者比值与病情轻重呈负相关关系,轻、中度慢性乙肝与中度慢性乙肝及重型慢性乙肝之间则已ALT/AST比值差异有显著性(P<0.05)。该结果提示:计算A/G与ALT/AST比值对慢性乙肝的临床分类及估计病情预后有着一定的帮助,该方法简单易行。

关 键 词:肝炎.乙型  白蛋白  球蛋白  丙氨酸转氨酶  门冬氨酸转氨酶

The Ratios of A/G and ALT/AST and Their Relation to the Severity of Chronic Hepatitis B
Xiang Longkui, Huang Yanqing, He Pingping, et al. The Ratios of A/G and ALT/AST and Their Relation to the Severity of Chronic Hepatitis B[J]. Medical Journal of Wuhan University, 1999, 20(4): 331-332
Authors:Xiang Longkui   Huang Yanqing   He Pingping   et al
Abstract:篢he ratios of A/G and ALT/AST in 148 cases of chronic hepatitis B were measured. The results showed thatthe ratios of A/G as well as ALT/AST decreased. The change of A/G and ALT/AST was in agreement with theprogress of chronic hepatitis B. The mechanisms of decrease of two ratios were discussed. The measurement ofthese ratios if helpful in the management of chronic hepatitis B.
Keywords:hepatitis B  albumin  globulin  alanine aminotransferase  aminotransferase  
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