高血压病人动态血压变异性与心室重构的关系研究

目的：探讨高血压病人动态血压变异性与心室重构的关系.方法：选择140例高血压患者为观察组,140例体检正常的人为对照组.比较两组24h平均收缩压、平均舒张压、24h血压变异性、舒张期左心室后壁厚度（LVPWT）、舒张期室间隔厚度（IVST）、左心室舒张末期内径（LVIDd）、左心室质量指数（LVMI）.结果：观察组24h平均收缩压、平均舒张压、收缩压标准差、舒张压标准差、LVPWT、IVST、LVIDd和LVMI分别为（131.85±14.77）mmHg、（80.57±9.24）mmHg、（12.26±3.13）和（8.94±2.52）、（10.74±3.15）mm、（11.87±1.92）mm、（53.14±7.39）mm、（45.24±5.18）g/m2,均显著高于对照组（P〈0.05）.结论：相比于正常人,高血压动态血压变异性更为显著,心室重构明显.

Research on relationship between ambulatory blood pressure variability andventricular remodeling in patients with hypertension

Objective： To study the relationship between ambulatory blood pressure variability and ventricular remodeling in patientswith hypertension. Methods： 140 cases of high blood pressure were selected in the observation group, 140 cases of normal people in thecontrol group. 24 h average systolic blood pressure and average diastolic pressure, 24 h blood pressure variability, diastolic left ventricularposterior wall thickness （LVPWT）, diastolic ventricular septal thickness （IVST）, left ventricular end-diastolic diameter （LVIDd）, leftventricular mass index （LVMI） of the two groups were compared. Results： 24 h average systolic blood pressure , average diastolic andsystolic blood pressure standard deviation, diastolic blood pressure standard deviation, LVPWT, IVST, LVIDd and LVMI of the observationgroup were respectively （131.85＋14.77） mm Hg, （80.57±9.24） mm Hg and 12.26±3.13 and 3.13, （10.74±3.15） mm, 2.52 mm （11.87±1.92） mm, （53.14±7.39） mm, （45.24±5.18） g/m2, significantly higher than those of the control group （P〈0.05）. Conclusion： Comparedwith the normal, high blood pressure ambulatory blood pressure variability is more significant with obvious ventricular remodeling.