同一校准品不能直接用于校正非配套检测系统

目的：观察同一校准品能否直接用于校正非配套检测系统。方法：以罗氏试剂及程序、罗氏cfas校准品、日立7060全自动生化分析仪为标准检测系统，用Beckman校准品的标示值直接校正奥林帕斯AU2700／中生试剂检测系统和Beckman Delta CX7／Beckman试剂检测系统；然后以新鲜病人混合血清作为临时校准品，Beckman校准品经标准系统准确度传递后，把Beckman校准品的标示值转换为校正“奥林帕斯AU 2700／中生试剂”测定系统的实际校正值，再用此值校正AU2700／中生试剂系统，在上述四个检测系统上同时测定40份新鲜病人血清的尿素(UREA)、肌肝(Cr)、糖(GLU)、钙(Ca)、镁(Mg)、尿酸(UA)、甘油三酯(TG)、胆固醇(CHOL)，并对所得结果进行均值及线性回归分析。结果：Beckman校准品的标示值直接校正AU2700／中生试剂系统时，各指标的均值与标准系统的均值相对偏倚超过5％的有UREA、Cr、Ca、TG，分别为7．89％，11．70％，9．00％，16．80％。Beckman Delta CX7检测系统准确度传递后的AU2700／中生试剂系统与标准测试系统相比，各指标均值相对偏倚均小于5％，同时线性回归良好。结论：同一校准品不能直接用于校正非配套检测系统，但同一校准品经过标准系统准确度传递后可用于校正其它非配套检测系统。

The Same Calibrator Can't Directly Calibrate the Different Analytic Systems

Objective To observe whether the same calibrator can directly calibrate the different analytic systems. Methods The standard system was composed of Roche reagent, Roche cfas calibrator and Hitachi 7060 automatic biochemical ana-lyzer. The indicative value of Beckman multi-calibrator calibrated directly Olympus AU 2700/Zhongsheng reagent system and Beckman Delta CX7/Beckman reagent system. Then the accuracy was transmitted to the fresh mixed patient sera from the standard system. The indicative value of the Beckman multi-calibrator was transferred into the actual value in the Olympus AU 2700/Zhongsheng system. UREA,Creatinine(Cr),glucose(GLU),Calcium(Ca),magnesium(Mg),uric acid (UA),triglyceride(TG) and cholesterol (CHOL)in 40 fresh sera were measured by the four analytic systems above men-tioned. The all results were analyzed by SPSS 11. 0 software. Results When Olympus AU 2700/Zhongsheng system was calibrated by the indicative value of the Beckman multi-calibrator,the relative bias of UREA,Cr,Ca,TG were above 5% between Olympus AU 2700/Zhongsheng and the standard system. Among Olympus AU 2700/Zhongsheng system whose accuracy was transmitted. Beckman Delta CX7 system and the standard system,the relative bias were all lower than 5%. Meanwhile,the linear regressions were good. Conclusions The same calibrator can't directly calibrate the different analyt-ic systems,but it can calibrate the other analytic systems when it's accuracy is transferred by the standard system.