皮层下动脉硬化性脑病血流动力学与血液流变学变化及其临床意义

摘要 目的：探讨皮层下动脉硬化性脑病(SAE)脑血流动力学与血液流变学变化及其临床意义。方法：对64例SAE患者进行经颅多谱勒(TCD)及血液流变学检查，并与同期60例健康老年人比较、分析。结果：SAE组TCD异常率明显高于对照组，主要表现为脑动脉硬化、脑供血不足、脑血管狭窄，SAE组血流变示血粘滞度增高，与对照组相比有显著差异(p<0.001)。结论： SAE患者存在明显的脑血流动力学与血液流变学异常。关键词 皮层下动脉硬化性脑病 经颅多谱勒 血液流变学

The changes of cerebral hemodynamic and hemorrheology in SAE

The changes of cerebral hemodynamic and hemorrheology in SAE The Dongfeng Affiliated Hospital of Yunyang Medical Collage,Shiyan,442008,Hubei Zhang-Runxi Xie-Binxuan Nie-Xin Xiong_Guilan Abstract Objective: To investigate the changes of cerebral hemodynamic and hemorrheology in patients with Subcortical arteriosclerotil encephalopathy(SAE). Methods: cerebral hemodynamic by Transcranial Doppler(TCD)and hemorrheology were carried out in 64 SAE cases and 60 healthy elderly,the date was analysed and compared. Results:The abnormality of TCD in SAE and healthy elderly respectively was 100% and 58%,the TCD mainly shows arteriosclerosis, decreased flow velocity and vessel stenosis, the blood viscosity was higher than those of the healthy elderly,these was siginificant difference between the two groups. Conclusions: there was obviously abnormality of cerebral hemodynamic and hemorrheology in SAE,these may be one of the facters in the progress of disease. Key words Subcortical arteriosclerotil encephalopathy ; hemorrheolog Transcranial Doppler