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乌索酸对大鼠胆汁的影响
引用本文:熊筱娟,陈蔚云,崔江龙,李开泉,陈武.乌索酸对大鼠胆汁的影响[J].中医药学报,2003,31(4):54-55.
作者姓名:熊筱娟  陈蔚云  崔江龙  李开泉  陈武
作者单位:1. 江西宜春学院,江西,宜春,336000
2. 江西医学院,江西,南昌,330006
3. 宜春市第一人民医院,江西,宜春,336000
基金项目:国家高技术研究发展计划 (863计划 )资助项目(2 0 0 2AA2Z32 1 7)
摘    要:目的:观察乌索酸对动物胆汁的影响。方法:采用麻醉大鼠行胆汁引流术,测定正常大鼠及APIT肝损伤大鼠的胆汁分泌量及胆汁成分,测定血清SB含量。结果:ig乌索酸正常大鼠及APIT模型大鼠的胆汁流量明显增加,胆汁中胆红素浓度提高,血清胆红素含量明显降低。结论:乌索酸有明显的利胆、促进胆红素排泄的作用。

关 键 词:乌索酸  利胆作用  胆汁流量  胆红素  动物实验
文章编号:1002-2392(2003)04-0054-02

Effect of usolic acid on promoting bile secretion in rat
XIONG Xiao-juan ,CHEN Wei-yun ,CEI Jang-long ,et al.Effect of usolic acid on promoting bile secretion in rat[J].Acta Chinese Medicine and Pharmacology,2003,31(4):54-55.
Authors:XIONG Xiao-juan  CHEN Wei-yun  CEI Jang-long  
Institution:XIONG Xiao-juan 1,CHEN Wei-yun 2,CEI Jang-long 3,et al
Abstract:Objective: To study the bile promoting secretion of ursolic acid administrated ig in rat.Methods:Ursolic was administrated ig to the rats with liver injury induced by APIT.SB in serum were examined.The bile folw rate and theconcentration of the main components in the bile of ratsafter ig adminstration of Ursolic acid were estimated.Results:Ursolic acid administrated ig decreased the serum SB levels in the rats treated with APIT,promoted thesecretion of bile and increased the concentration ofbilirubin in the bile.Conclusion:Ursolic acid administratedig exhibited significant promoting bile secretion. Author's address:1.Yichun University,Yichun 336000,China;2.Jiangxi Medical University,Nanchang 330006,China;3.The First People's Hospital of Yichun District,Yichun 336000,China
Keywords:Ursolic acid  Promoting bile secretion  biliru-bin APIT  
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