经阴道超声弹性成像对宫颈癌诊断的临床应用初探

目的 探讨实时经阴道超声弹性成像在宫颈病变诊断中的临床应用价值.方法 分析124例宫颈病变患者的超声弹性图像,所有病例均经手术或组织活检病理证实.计算病变区与周围组织的弹性应变比值(strain ratio),以病理结果为金标准进行良恶性病变比较,采用ROC曲线分析strain ratio在诊断宫颈病变中的最佳截断值.结果 良性病变的弹性图像以绿色渲染为主,平均strain ratio值为2.71±1.56;恶性病变者渲染为蓝色,平均strain ratio为8.32±4.11,二者差异有统计学意义(P＜0.01).ROC 曲线显示当选取strain ratio为4.99时,曲线下面积最大达0.912,特异性和灵敏性分别为80.7％和89.6％.结论 实时超声弹性成像为宫颈病变良、恶性的鉴别诊断提供了一种新的无创检查方法.

Preliminary study of transvaginal elastography in diagnosing cervical cancers

Objective To investigate the clinical value of transvaginal elastography in diagnosing cervical cancers.Methods Totally,124 patients of cervical lesions with definite pathological results were enrolled.Elastograms were collected and the strain ratios of the benign and malignant lesions were record and compared.ROC curve was used to find the best cut-off point.Results Elastography was useful in differentiating benign and malignant lesions by different color.Values of strain ratio of different pathological lesions were statistically different ( P ＜0.01).The mean value of strain ratio was 2.71 ± 1.56 for benign lesions and 8.32 ± 4.11 for malignant ones.The best cut-off point was 4.99 basing on the ROC curve.The sensitivity and specificity were 80.7％ and 89.6％,respectively.Conclusions Real-time transvaginal elastography was a new way in differential diagnosing cervical cancers from benign lesions of the cervix.