Platelets and blood vessels: the adhesion event. |
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| Authors: | G J Roth |
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| Affiliation: | Hematology Section, Seattle Veterans Hospital, WA. |
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| Abstract: | Circulating blood platelets attach to damaged blood vessels by specific adhesion molecules. In the human arterial circulation, a unique 'shear-dependent' mechanism governs adhesion by a single receptor-ligand (glycoprotein Ib-von Willebrand factor) pair. Here, Gerald Roth reviews recent data that provide insights into the functions of these molecules. |
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