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骨髓活检在慢性粒细胞白血病中的临床意义
引用本文:鲁志英,李良凤,张万胜,邓明凤.骨髓活检在慢性粒细胞白血病中的临床意义[J].中国医师进修杂志,1999(3).
作者姓名:鲁志英  李良凤  张万胜  邓明凤
作者单位:湖北省荆州市中心医院血液实验室
摘    要:对32例慢性粒细胞白血病(CML)患者进行骨髓组织病理学检查,应用Bartl及Frisch等提出的分型标准,将32例CML分为GRAN型及GRAN/MEG混合型。GRAN型巨核细胞正常或降低,骨纤程度轻,且生存期长。而GRAN/MEG混合型,巨核细胞明显增多,骨纤程度重,临床治疗效果差,生存期短

关 键 词:慢性粒细胞性白血病  骨髓活检  巨核细胞  骨髓纤维化  生存

THE CLINICAL SIGNIFICANCE OF BONE MARROW BIOPSY IN CHRONIC MYELOID LEUKEMIA
Lu Zhiying,Li Liangfeng,Zhang Wansheng et al.THE CLINICAL SIGNIFICANCE OF BONE MARROW BIOPSY IN CHRONIC MYELOID LEUKEMIA[J].Chinese Journal of Postgraduates of Medicine,1999(3).
Authors:Lu Zhiying  Li Liangfeng  Zhang Wansheng
Institution:Lu Zhiying,Li Liangfeng,Zhang Wansheng et al.Department of Hematology,Hubei Province Jingzhou Central Hospital,Jingzhou 434100
Abstract:In this paper,bone marrow histopathology from 32 patients of chronic myeloid leukemia,might be divided into GRAN type and GRAN/MEG type in according to the classification standard introduced by Bartl and Frisch etc.The GRAN type the numbers of megakaryocvtes are normal or decreased,myelofibrosis degree is light and the longer survival time,but the GRAN/MEG type the numbers of megakaryocvtes are signal increased,myelofibrosis degree is serious,clincal efficacy bad and the shorter survival time.
Keywords:Chronic myeloid leukemia\ Bone marrow biopsy\ Megakaryocvte \ Myelofibrosis\ Survival
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