| 亚超细汉麻粉体生物相容性研究 |
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| 引用本文： | 张森,张宏杰,张琦,尚曼,钟智丽,刘艳霞.亚超细汉麻粉体生物相容性研究[J].天津医科大学学报,2012,18(2):181-184. |
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| 作者姓名： | 张森 张宏杰 张琦 尚曼 钟智丽 刘艳霞 |
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| 作者单位： | 1. 天津医科大学药理学教研室,天津,300070
2. 天津工业大学纺织学院,天津,300387 |
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| 摘 要： | 目的:评价亚超细汉麻粉体的生物相容性.方法:按照GB/T16886的评价要求,对亚超细汉麻粉体进行细胞毒性试验、皮肤刺激试验和致敏试验.结果:6.25％亚超细汉麻粉体浸提液的细胞毒性为1级,12.5％、25％亚超细汉麻粉体浸提液的细胞毒性为2级,50％、100％亚超细汉麻粉体浸提液的细胞毒性大于2级；亚超细汉麻粉体没有皮肤刺激和致敏现象.结论:6.25％亚超细汉麻粉体浸提液有极轻的细胞毒性,无皮肤刺激和致敏现象,6.25％亚超细汉麻粉体符合生物相容性要求.
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| 关 键 词： | 亚超细汉麻粉体 生物相容性 细胞毒性 皮肤刺激 致敏实验 |
Experimental studies on biocompatibility of hemp powder with submicron-scale |
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| ZHANG Sen
,
ZHANG Hong-jie
,
ZHANG Qi
,
SHANG Man
,
ZHONG Zhi-li
,
LIU Yan-xia.Experimental studies on biocompatibility of hemp powder with submicron-scale[J].Journal of Tianjin Medical University,2012,18(2):181-184. |
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| Authors: | ZHANG Sen ZHANG Hong-jie ZHANG Qi SHANG Man ZHONG Zhi-li LIU Yan-xia |
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| Institution: | 1(1.Department of Pharmacology,Tianjin Medical University,Tianjin 300070,China;2.College of Textiles,Tianjin Polytechnic University,Tianjin 300387,China) |
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| Abstract: | Objective: To evaluate the biocompatibility of hemp powder with submicron-scale.Methods: According to the standard for the biological evaluation of the GB/T16886,cytotoxicity test,dermal irritation test and sensitization test were carried out to evaluate the biocompatibility of hemp powder with submicron-scale.Results: The results showed that the level of the cytotoxicity of 6.25% hemp powder with submicron-scale extract group was 1 degree;the level of the cytotoxicity of 12.5%,25% hemp powder with submicron-scale extract group was 2 degree;50%,100% hemp powder with submicron-scale extract group was more than 2 degree.No obvious dermal irritation and sensitization.Conclusion: 6.25% hemp powder with submicron-scale has little cytotoxicity,no obvious dermal irritation and sensitization.6.25% hemp powder with submicron-scale meets the biocompatibility requirements. |
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| Keywords: | hemp powder with submicron-scale biocompatibility cytotoxicity dermal irritation sensitization |
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