Activation of a novel medullary pathway elicits a vagal,cholinergic bronchoconstriction in guinea-pigs |
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| Affiliation: | Department of Allergy and Inflammation, Schering-Plough Research, New Jersey, USA |
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| Abstract: | Electrical stimulation of structures within the rostral region of the dorsal medulla of the guinea-pig activates a vagal cholinergic bronchoconstriction pathway and simultaneously activates a sympathetic inhibitory input. Removal of the latter by spinal section potentiated CNS-induced bronchospasm. |
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