Characteristics of the metabolic disorders during prolonged craniofacial surgery]

Brain and liver metabolism has been studied by selective probing of vessels collecting blood from the brain and liver, in 95 patients with various surgical craniofacial pathology. Prolonged general anesthesia in craniofacial traumas has a negative effect on brain metabolism. Changes in indispensible amino acid formulas and hypoxia may cause the loss of brain circulation autoregulation and damages in central mechanisms regulating metabolic processes. A complex scheme of metabolism correction during prolonged anesthesia in craniofacial surgery is suggested.