Effectiveness of honey dressing in the treatment of diabetic foot ulcers: A systematic review and meta-analysis |
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| Institution: | 1. College of Chemical Engineering, Shijiazhuang University, Hebei Province, Shijiazhuang 050035, China;2. Department of Basic Science, Hebei College of Industry and Technology, Hebei Province, Shijiazhuang 050035, China;1. Department of Surgery, University Hospital and Faculty of Medicine, Slovak Medical University, Bratislava, Slovakia;2. University Hospital of the Merciful Brothers, Bratislava, Slovakia;3. Institute of Zoology, Slovak Academy of Sciences, Bratislava, Slovakia;4. Scientica, s.r.o., Bratislava, Slovakia;5. Department of Microbiology, Faculty of Medicine, Slovak Medical University, Bratislava, Slovakia;1. Department of Medicine, Kasturba Medical college, Mangalore, Manipal University, India;2. Department of Microbiology, Kasturba Medical college, Mangalore, Manipal University, India;3. Department of Surgery, Kasturba Medical college, Mangalore, Manipal University, India;4. Department of Pharmacology, Kasturba Medical college, Mangalore, Manipal University, India;5. Department of Medicine, Yenepoya Medical College, Mangalore, Yenepoya University, India;1. Tissue Engineering Laboratory, PSG Institute of Advanced Studies, Coimbatore, Tamil Nadu, India;2. Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam, Erode, Tamil Nadu, India |
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| Abstract: | ObjectiveHoney dressing has been applied in the treatment of diabetic foot ulcers (DFUs). However, there is a lack of research showing ample evidence that honey dressing is more effective in the treatment of DFUs than other dressings. This study aimed to examine the effects of honey dressing on wound-healing process for DFUs.MethodWe searched for evidence regarding honey dressing used in the treatment of DFUs in various databases. We selected randomized controlled trials (RCTs) and quasi-experimental studies for meta-analysis.ResultsThe meta-analysis showed that honey dressing effectively shortened the wound debridement time, wound healing time, and bacterial clearance time; it increased the wound healing rate and bacterial clearance rate during the first one to two weeks of use.ConclusionOur findings suggest that honey dressing effectively promotes healing in DFUs. Further research is needed to elucidate these findings so that this form of treatment can be widely applied. |
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| Keywords: | Honey dressing Diabetic foot ulcers Systematic review Meta-analysis |
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