| 山楂药用价值与上市药品研究进展 |
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| 引用本文： | 贾彬,麦子盈,陈启文,覃思意,王乐琪,严诗楷,李莎莎,肖雪. 山楂药用价值与上市药品研究进展[J]. 中草药, 2023, 54(20): 6878-6888 |
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| 作者姓名： | 贾彬 麦子盈 陈启文 覃思意 王乐琪 严诗楷 李莎莎 肖雪 |
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| 作者单位： | 广东药科大学 广东省代谢病中西医结合研究中心(中医药研究所), 广东 广州 510006;国家药品监督管理局药品快速检验技术重点实验室(广东省药品检验所), 广东 广州 510663;广东药科大学 广东省代谢病中西医结合研究中心(中医药研究所), 广东 广州 510006;广州中医药大学第二附属医院, 广东 广州 510120;广东药科大学 广东省代谢病中西医结合研究中心(中医药研究所), 广东 广州 510006;上海交通大学药学院, 上海 200240;国家药品监督管理局药品快速检验技术重点实验室(广东省药品检验所), 广东 广州 510663;上海交通大学药学院, 上海 200240;国家药品监督管理局药品快速检验技术重点实验室(广东省药品检验所), 广东 广州 510663;广州中医药大学第二附属医院, 广东 广州 510120 |
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| 基金项目： | 广州市科技计划项目珠江科技新星专项（201610010113）；国家药品监督管理局药品快速检验技术重点实验室开放课题（KF2022002，KF2022006） |
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| 摘 要： | 山楂Crataegus pinnatifida属蔷薇科植物，其果实、叶、种子、根等均具有极高的价值，在医药、食品、化工等领域均有较广泛的应用。山楂不同部位的药用功效主要用于治疗心脑血管疾病、代谢性疾病、细菌感染等。随着研究逐步深入，现已有多种相关药品上市，并在临床上得到广泛使用。通过对山楂不同入药部位进行分类整理，按药理作用分别对其上市药品的临床应用、基础研究及质量研究等进行综述，探讨山楂在开发大健康产品方面的优势，为山楂的综合利用与开发提供参考。
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| 关 键 词： | 山楂 上市药品 质量标准 大健康产品开发 药用功效 |
| 收稿时间： | 2023-05-10 |
Research progress on medicinal value of Crataegi Fructus and related marketed drugs |
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| JIA Bin,MAI Zi-ying,CHEN Qi-wen,QIN Si-yi,WANG Le-qi,YAN Shi-kai,LI Sha-sh,XIAO Xue. Research progress on medicinal value of Crataegi Fructus and related marketed drugs[J]. Chinese Traditional and Herbal Drugs, 2023, 54(20): 6878-6888 |
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| Authors: | JIA Bin MAI Zi-ying CHEN Qi-wen QIN Si-yi WANG Le-qi YAN Shi-kai LI Sha-sh XIAO Xue |
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| Affiliation: | Guangdong Metabolic Disease Research Center of Integrated Chinese and Western Medicine (Institute of Traditional Chinese Medicine), Guangdong Pharmaceutical University, Guangzhou 510006, China;Key Laboratory for Rapid Testing Technology of Drugs of National Medical Products Administration, Guangdong Institute for Drug Control, Guangzhou 510663, China;Guangdong Metabolic Disease Research Center of Integrated Chinese and Western Medicine (Institute of Traditional Chinese Medicine), Guangdong Pharmaceutical University, Guangzhou 510006, China;The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China;Guangdong Metabolic Disease Research Center of Integrated Chinese and Western Medicine (Institute of Traditional Chinese Medicine), Guangdong Pharmaceutical University, Guangzhou 510006, China;College of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai 200240, China;Key Laboratory for Rapid Testing Technology of Drugs of National Medical Products Administration, Guangdong Institute for Drug Control, Guangzhou 510663, China;College of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai 200240, China;Key Laboratory for Rapid Testing Technology of Drugs of National Medical Products Administration, Guangdong Institute for Drug Control, Guangzhou 510663, China;The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China |
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| Abstract: | Shanzha (Crataegi Fructus) is a plant belongs to the Rosaceae family. Its fruits, leaves, seeds, and roots all have high value and are widely used in the fields of medicine, food, and chemical industry. The medicinal properties of different parts of Crataegi Fructus are mainly focused on cardiovascular and cerebrovascular diseases, metabolic disorders, and bacterial infections. With in-depth research, multiple related drugs have been introduced to the market and widely used in clinical practice. By organizing and classifying the different medicinal parts, this study provides a review of the clinical applications, basic research, and quality studies of the marketed drugs based on their pharmacological effects. Furthermore, it explores the advantages of Crataegi Fructus in developing products for overall health, providing a reference for the comprehensive utilization and development of Crataegi Fructus. |
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| Keywords: | Crataegi Fructus marketed drugs quality standard great health product development medicinal effect |
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