| NTRK重排宫颈肉瘤的病例报告及文献复习 |
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| 引用本文： | 李晓琦,吴小华,刘帅,陆静,吴洪斌,温灏. NTRK重排宫颈肉瘤的病例报告及文献复习[J]. 肿瘤药学, 2023, 13(4): 515-520 |
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| 作者姓名： | 李晓琦 吴小华 刘帅 陆静 吴洪斌 温灏 |
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| 作者单位： | 1.复旦大学附属肿瘤医院,肿瘤妇科,上海,200032;2.复旦大学附属肿瘤医院,核医学科,上海,200032;3.复旦大学附属肿瘤医院,放射诊断科,上海,200032;4.复旦大学附属肿瘤医院,药剂科,上海,200032 |
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| 摘 要： | 本研究报道了2例年轻女性NTRK重排宫颈肉瘤的病例,通过分析患者的术前临床表现、影像学检查、结合宫颈肿块切除的病理诊断确诊。2例患者均采用手术治疗切除子宫,总体疾病无进展生存时间分别为20个月和11个月。本文通过复习近年来国内外相关报道,总结NTRK重排宫颈肉瘤的最新治疗进展。
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| 关 键 词： | NTRK重排 宫颈肉瘤 手术治疗 靶向治疗 |
Case reports of NTRK-rearranged cervical sarcomas and literature review |
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| LI Xiaoqi,WU Xiaohu,LIU Shuai,LU Jing,WU Hongbin,WEN Hao. Case reports of NTRK-rearranged cervical sarcomas and literature review[J]. Anti-Tumor Pharmacy, 2023, 13(4): 515-520 |
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| Authors: | LI Xiaoqi WU Xiaohu LIU Shuai LU Jing WU Hongbin WEN Hao |
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| Affiliation: | 1.Department of Gynecological Oncology,;2.Department of Nuclear Medicine,;3.Department of Radiology,;4.Department of Pharmacy, Fudan University Shanghai Cancer Center, Shanghai, 200032, China |
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| Abstract: | This study reported two cases of young women with NTRK-rearranged cervical sarcomas. The diagnosis was confirmed by analyzing the preoperative clinical manifestations, imaging examination, and pathological features of cervical sarcomas excision. Both patients underwent hysterectomy, and the overall disease progression-free survival was 20 and 11 months, respectively. In this paper, we also reviewed the related literature published in recent years, and summarized the latest progress in the treatment of NTRK-rearranged cervical sarcomas. |
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| Keywords: | NTRK-rearranged Cervical sarcoma Surgical treatment Targeted therapy |
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