慢性高原病的脑磁共振弥散张量成像研究 |
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引用本文: | 任方远,;蔡琳,;王悦,;刘光耀,;郝晓东,;高崎炜.慢性高原病的脑磁共振弥散张量成像研究[J].西北国防医学杂志,2014(4):308-310. |
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作者姓名: | 任方远 ;蔡琳 ;王悦 ;刘光耀 ;郝晓东 ;高崎炜 |
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作者单位: | [1]兰州军区兰州总医院影像诊断科,甘肃兰州730050; [2]兰州军区兰州总医院信息科;,甘肃兰州730050; [3]武警甘肃总队医院妇产科,甘肃兰州730050; |
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基金项目: | 甘肃省自然科学基金资助项目(145RJZA081) |
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摘 要: | 目的:应用3.0T磁共振弥散张量成像(diffusion tensor imaging,DTI)技术,评价慢性高原病患者脑白质的各向异性分数(fractional anisotrophy,FA)。方法:本研究共包括9例慢性高原病患者和10例正常志愿者,行常规MRI扫描及DTI扫描,测定DTI图像上不同脑白质区的FA值,并比较两组FA值的差异。结果:两组常规MR检查未见明确差异,DTI示慢性高原病组双侧额叶及海马旁白质、胼胝体膝部FA值较正常志愿者组降低,差异具有统计学意义(P〈0.05)。结论:慢性高原病患者部分脑白质区FA值下降,提示脑白质纤维束完整性受损。
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关 键 词: | 磁共振成像 认知障碍 慢性高原病 |
Application of the diffusion tensor imaging in chronic mountain sickness |
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Institution: | REN Fang-yuan,CAI Lin,WANG Yue , et al. (Department of Imaging Diagnosis, Lanzhou General Hospital of Lanzhou Military Area Command, Lanzhou 730050,China) |
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Abstract: | Objective:To evaluate the fractional anisotrophy(FA)value of white matter in patients with chronic mountain sickness(CMS)with diffusion tensor imaging(DTI)on 3.0TMR.Methods:Ten normal controls(NC)and nine patients with CMS underwent conventional MRI and DTI.FA values were measured in different brain regions and then were compared between the two groups.Results:FA value decreased in both sides of the white matters of frontal lobe and parahippocampal gyrus,genu of corpus callusum in patients with CMS in contrast with NC.Conclusion:FA value of a part of white matter decreased,indicating the impairment of the microstructure of the white matter integrity in CMS. |
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Keywords: | Magnetic resonance imaging Cognitive impairment Chronic mountain sickness |
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